Ends on March 1, 2019

2019 American Cancer Society IRG Pilot Awards

Amount: $30,000

Due Date: March 1, 2019 @ 11:59PM


1. The purpose of this grant is to provide seed money (up to $30,000 for one year) for the initiation of promising new projects or novel ideas by new Yale Assistant Professors so that they can obtain preliminary results to enable them to compete successfully for national cancer research grants. Investigators who have obtained a competitive national research grant are not eligible for support through this mechanism, unless such a grant is primarily for faculty salary. Recipients of previous ACS-IRG Awards, recipients of research grants obtained from National Foundations, recipients of research funds from the tobacco industry, and established investigators are also ineligible.

YCC members and non-members are encouraged to apply. Applications in all areas of cancer research are encouraged: basic, translational, clinical, population and control. Each applicant can submit only a single proposal for this competition in any year. Applications will be ranked based on scientific excellence, innovation, cancer relevance, and likelihood to develop into nationally-funded cancer research. All funds must be expended in one year, and the scope of the proposal must reflect this. Because of the short duration and the size of these awards, they are not intended to support clinical trials or long-term clinical studies. However, they can be used to support analysis of data or material acquired in ongoing or completed clinical studies.  

2.  Applicants must be, at the time of the application, citizens or non-citizen nationals of the U.S. or its possessions and territories, or must have been lawfully admitted to the U.S. for permanent residence at the time of application. Permanent residents must submit, with the application, notarized evidence indicating that the candidate is in possession of an Alien Registration Receipt Card or has been approved for the issuance of such card as evidenced by an official passport stamp of the U.S. Immigration Service and that the form number of the card is I-551.

3.  Proposals in all areas of research into the biology, epidemiology, prevention, and/or treatment of cancer will be considered. The relevance of the project to the cancer problem must be explicitly described in the proposal.

 4.  A budget page must be submitted with the application, with justification for each category requested. The Business Manager from your department must sign the bottom of the budget page to confirm that s/he is aware of your application. Award term is April 15, 2019 - April 14, 2020. Budget form can be downloaded from this link: http://www.yalecancercenter.org/research/2019-acs.aspx 

5.  Awards are limited in size and are not designed to provide full-time technical help. Occasional technical support (for items such as the preparation of pathological specimens, photographic expertise, setting up extensive experiments, etc.) may be needed, and in such instances limited technical support may be awarded. Support of a full-time technician for a brief period of time is usually unrewarding in terms of accomplishment and frequently represents subsidization of ongoing programs, and is therefore not allowed.

6.  Patents. Grants are made with the understanding that patents will not be applied for in connection with any discovery made under grants awarded by the American Cancer Society without the prior written consent of the Society. More information on the ACS patent policy may be obtained from the YCC Office, WWW205.

7.  Ownership of Equipment. Title to equipment purchased under an American Cancer Society-Institutional Research Grant shall be vested in YCC.

8.  All proposals using vertebrate animals or human subjects must be reviewed by the YACUC or HIC, respectively, before the proposal will be funded.

9.  Publications resulting from research supported by the ACS must contain an acknowledgment, such as “Supported by Grant #IRG 17-172-57 from the American Cancer Society.”

10. Progress reports are required. Successful candidates will be informed when reports are due, and award recipients must provide the requested information in a timely fashion.

11.  Subsequent to the end date of the award or upon request, YCC must be informed of papers and/or grants resulting from this ACS-IRG award.

Expenditures Allowed

  • Research supplies and animal purchase and maintenance
  • Limited technical assistance
  • Domestic travel when necessary to carry out the proposed research program
  • Publication costs, including reprints
  • Costs of computer time
  • Special fees (pathology, photography, flow cytometry, sequencing, etc.)
  • Stipends for graduate students and postdoctoral assistants if their role is to promote and sustain the project presented by the junior faculty member
  • Equipment costing less than $2,000 (special justification is necessary for items exceeding this amount)
  • Registration fees at scientific meetings

 Expenditures Not Allowed

  • Salary of pilot project principal investigator
  • Secretarial/administrative salaries
  • Tuition
  • Foreign travel (special consideration given for attendance at scientific meetings held in Canada)
  • Honoraria and travel expenses for visiting lecturers
  • Books and periodicals
  • Membership dues
  • Office and laboratory furniture
  • Office equipment and supplies
  • Rental of office or laboratory space
  • Recruiting and relocation expenses
  • Non-medical services to patients
  • Per-diem charges for hospital beds
  • Construction, renovation, or maintenance of buildings/laboratories


1.  Budget page signed by department Business Manager. This application does not need to be submitted to the office of Grants & Contracts. Use non-federal fringe rates. It is expected that the funds will be expended in full during the one-year duration of the grant.  Spending will be monitored by YCC and unspent funds may be reclaimed by YCC if spending lags significantly. ACS-IRG grants cannot be extended. Budget form can be downloaded from this link: http://www.yalecancercenter.org/research/2019-acs.aspx 

2.  New NIH five-page biosketch:  OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020). https://grants.nih.gov/grants/forms/biosketch.htm

3.  Complete listing of all other support, active and pending. Include all local and institutional sources and grants. Use NIH format. https://grants.nih.gov/grants/forms/othersupport.htm

4.  YACUC and/or IRB protocol number(s), approval date, and title (if applicable). For studies requiring IRB approval, it is expected that an IRB protocol will be submitted within one month of award notification. YCC must be notified when such protocols are submitted and approval is received.

5.  Abstract of proposed research (400 word maximum). Do not include figures or references here.

6.  Research Proposal.  Description of project: three pages, maximum, including figures; single-spaced; Arial, Helvetica, or TNR 11 pt font or larger; margins at least 0.5 inch all around; your name must appear on every page. Abstract and references do not count toward page limit. There is no form page for this section.

7.  Letter of support signed by department chairman or section head. This letter should provide information regarding your departmental mentoring program, including the name (s) of your formal mentor and a description of mentoring activities.  Letter(s) of support should also be provided by any essential collaborator(s).

8.  Letter of support from your cancer research mentor.  This letter must indicate that the mentor has read the proposal and provided advice to the applicant during the development of the proposal. It must also indicate that your cancer research mentor will meet with you on a quarterly basis to discuss progress and future plans.  Please contact Dr. Joann Sweasy (joann.sweasy@yale.edu) if you need help with the identification of a cancer research mentor.

9. Provide up to two different reprints or manuscripts relevant to the current proposal may be submitted as part of the PDF. Hard copies of reprints are not needed.